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Wells syndrome is a rare condition of unknown cause. It is also called 'eosinophilic cellulitis'.

Typically the rash is preceded by itching or burning skin and consists of markedly swollen nodules and plaques (lumps) with prominent borders. The patches are usually bright red at first, frequently looking like cellulitis, then fade over four to eight weeks, leaving green, grey or brown patches. They can blister. The rash most commonly occurs on the limbs, but may also affect the trunk.

The patient often feels very tired and has a fever in approximately 25% of cases.

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