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Hereditary hemorrhagic telangiectasia are inherited as an autosomal dominant trait.

Punctate, somewhat domed, spider-like or linear telangiectasia are found anywhere on the body, but are especially common on the face. Lip involvement is typically a prominent feature, as is involvement of the nasal septum, leading to recurrent epistaxis.

Internal large vessel abnormalities can also be associated.

Gastrointestinal hemorrhage may occur.

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