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Transient acantholytic dermatosis is an acquired disease showing acantholytic dyskeratosis very similar to that seen in keratosis follicularis (Darier's disease) and benign familial chronic pemphigus (Hailey-Hailey disease).

Usually on the trunk of middle-aged men, there is a sudden eruption of pruritic erythematous scaling papules, coalescing into plaques.

Many lesions have an eroded surface from the breakage of subclinical or clinical vesicles.

Sweating is a known precipitating factor.

Usually clearing within months, some eruptions run a more chronic relapsing course.

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