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The Gianotti Crosti Syndrome is a characteristic response of the skin to viral infection in which there is a papular rash which lasts for several weeks.

Crosti Syndrome mainly affects children between the ages of 6 months and 12 years.

A clustering of cases is often observed.

A preceding upper respiratory infection is common.

Over the course of 3 or 4 days a profuse eruption of dull red spots develops first on the thighs and buttocks, then on the outer aspects of the arms, and finally on the face.

The rash is often asymmetrical.

The individual spots are 5-10 mm in diameter and are a deep red color.

Later they often look purple, especially on the legs, due to leakage of blood from the capillaries.

Itch is uncommon, particularly if hepatitis B is the cause.

The patient may feel quite well or have a mild temperature.

Mildly enlarged lymph nodes in the armpits and groins may persist for months.

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