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Donovanosis is a mildly contagious, chronic, indolent, progressive, autoinoculable, ulcerative disease involving the skin and lymphatics of the genital and perianal areas.



Causes:

Poorly understood. Mildly contagious. Repeated exposure necessary for clinical infection to occur. In most cases, lesions cannot be detected in sexual contacts.

Men are affected more than twice as often as women, with most infections occurring in people aged 20-40 years. The disease is seldom seen in children or the elderly.

It is thought that anal intercourse, rather than vaginal intercourse, is the most frequent source of infection. About 50% of infected men and women have lesions in the anal area.



Symptoms:

Small, painless nodules appear after about 10*40 days of the contact with the bacteria. Later the nodules burst, creating open, fleshy, oozing lesions. The infection spreads, mutilating the infected tissue. The infection will continue to destroy the tissue until treated. The lesions occur at the region of contact typically found on the shaft of the penis, the labia, or the perianal region. Rarely, the vaginal wall or cervix is the site of the lesion.

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