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M.ulcerans infection occurs at sites of traumatic inoculation, usually the legs, resulting in large to gigantic deep painless ulcerations, occurring in tropical regions of Africa and Australia.



Causes:

The infection is transmitted from the environment to people by unknown mechanism. Mycobacterium Ulcerans is not spread from person to person.


Symptoms:

* The infection generally starts as a small spot attached to the skin resembling a mosquito bite that enlarges over days to weeks.

* Acute swelling of the whole limb.

* A nodule beneath the skin may be the first sign.

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